Human Mammary Epithelial Cells: HMEpC 人乳腺上皮細胞

產品型號: 830K-05A_830-05a

HMEpC from Cell Applications, Inc. have been utilized in numerous research publications, for example to:
  • Investigate the role of exosomes secreted by cancer cells in formation of tumor permissive microenvironment through manipulation of normal mammary epithelium
  • Serve as control in a study investigating antitumor properties of cannabinoids and stem cell microenvironment
  • Determine that differential expression of glycoproteins allows classification of human breast cells into normal, benign, malignant, basal, and luminal groups
  • Identify ALDH isoform 5A1 as a potential target for treatment of human breast ductal carcinoma
  • Determine that combination of an anti-growth factor treatment using phototherapy (UV-B) is more effective
  • Investigate cell survival following DNA damage
  • Show the important roles of tumor suppressors in mammary epithelial differentiation
  • Explain protection of extracellular matrix from degradation in normal mammary epithelia,
  • Show that Maspin loss in metastatic cancer leads to unrestricted ECM degradation, contributing to metastasis, and that loss of EcSOD expression also promotes invasiveness by disrupting ECM
  • Investigate the role of shortened telomeres in initiation of genomic instability, cytokinesis failure and polyploidy
  • Elucidate the role of Myc in malignancy by studying its ability to transform primary epithelial cells
  • Demonstrate, along with Human dermal Fibroblasts, also from Cell Applications, Inc., that resveratrol inhibits mono-ubiquitination of histone H2B

 

 

 

DETAILS

Tissue Normal healthy human mammary glands
QC No bacteria, yeast, fungi, mycoplasma, virus
Bioassay Attach, spread, proliferate in Growth med
Cryovial 500,000 HMEpC (5th passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO
Kit Cryovial frozen HMEpC(830-05a), Growth Med (815-500), Subculture Rgnt Kit (090K)
Proliferating Shipped in Gr Med, 6th psg (flasks or plates)
Doublings At least 16
Applications Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.

 

PRODUCTS

PRODUCT SIZE CAT.#
Cryopreserved HMEpC, Adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) 1 Kit 830K-05a
Cryopreserved HMEpC, Adult: Frozen HMEpC (5x10^5) 1 Cryovial 830-05a
Proliferating HMEpC, Adult: Actively growing, dividing cells in medium T-25 Flask 831-25a
Proliferating HMEpC, Adult: Actively growing, dividing cells in medium T-75 Flask 831-75a

 

RELATED PRODUCTS

PRODUCT SIZE CAT.#
HMEpC Growth Medium: All-in-one ready-to-use 500 ml 815-500
HMEpC Growth Medium Kit: Basal medium & growth supplement sold together packaged separately Yields 500 ml 815K-500
HMEpC Basal Medium: Basal medium (contains no growth supplement).  Add GS before use. 500 ml 814-500
HMEpC Growth Supplement: Added to Basal Medium to create Growth Medium 5 ml 815-GS

 

EXTENDED FAMILY PRODUCTS

PRODUCT SIZE CAT.#
Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 1 Kit 090K
HMEpC RNA, Adult: Total RNA prepared from Human Mammary Epithelial Cells, adult 10 ug 830-R10a
HMEpC RNA, Adult: Total RNA prepared from Human Mammary Epithelial Cells, adult 25 ug 830-R25a
Monoclonal IL-1 Receptor Antagonist Antibody: Monoclonal IL-1 Receptor Antagonist Antibody 100 ul CB19846
Freezing Medium: For general cryopreservation of most primary cells. Contains FBS & DMSO. 50 ml 040-50
Cytofect™ Epithelial Cell Transfection Kit: 124 x 24-Well Rxns 1 Kit TF102K
Cytofect™ Epithelial Cell Transfection Kit: 25 x 24-Well Rxns 1 Sample Kit TF102KS
Cyto-X Cell Counting Reagent: 500 tests 1 Bottle 028-01
Cyto-X Cell Counting Reagent Sample: 100 tests Sample 028-S
Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor 100 ug RP1026-100
Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor 500 ug RP1026-500
Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor 1000 ug RP1026-1000
Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha 10 ug RP1173-10
Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha 100 ug RP1173-100
Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha 1000 ug RP1173-1000
Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free 100 ug RP1026AF-100
Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free 500 ug RP1026AF-500
Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free 1000 ug RP1026AF-1000
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