Human Chondrocytes: Rheumatoid Arthritis: HC-RA 人類軟骨細胞：類風濕性關節炎：HC-RA
產品型號： 402RAK-05a
Human Chondrocytes Rheumatoid Arthritis (HC-RA) are derived from human articular cartilage of donors with rheumatoid arthritis (RA). Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in RA cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-RA can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-RA can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies.
DETAILS
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Tissue
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Human articular cartilage, from donor w/ rheumatoid arthrits
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QC
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No bacteria, yeast, fungi, mycoplasma, virus |
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Bioassay
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Attach, spread, proliferate in Growth Med |
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Cryovial
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500,000 HC-RA (1st passage) frozen in Basal Medium w/10% FBS, 10% DMSO
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Kit
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Cryovial frozen HC-RA (402RA-05), Growth Medium (411-500), Subcltr Rgnt Kit (090K)
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Proliferating
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Shipped in Gr Med, 2nd psg (flasks or plates)
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Doublings
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At least 10
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Applications
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Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
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PRODUCTS
| PRODUCT | SIZE |
CAT.# |
| Cryopreserved HC-RA, Adult: 5x10^5 Cells (from donor with Rheumatoid Arthritis, Adult), Medium & Subculture Reagents (See Details tab for specifics) | 1 Kit |
402RAK-05a |
| Cryopreserved HC-RA, Adult: Frozen HC from donor with Rheumotoid Arthritis (5x10^5) | 1 Cryovial |
402RA-05a |
| Proliferating HC-RA, Adult: Actively growing, dividing cells from donor with Rheumatoid Arthritis, in medium | T-25 Flask |
403RA-25a |
| Proliferating HC-RA, Adult: Actively growing, dividing cells from donor with Rheumatoid Arthritis, in medium | T-75 Flask |
403RA-75a |
RELATED PRODUCTS
| PRODUCT | SIZE | CAT.# |
| HC Growth Medium: All-in-one ready-to-use | 500 ml | 411-500 |
| HC Growth Medium Kit: Basal medium & growth supplement sold together packaged separately | Yields 500 ml | 411K-500 |
| HC Basal Medium: Basal medium (contains no growth supplement). Add GS before use. | 500 ml | 410-500 |
| HC Growth Supplement: Added to Basal Medium to create Growth Medium | 50 ml | 411-GS |
| HC Differentiation Medium: Promotes cells to change from one type to another, more specialized | 250 ml | 411D-250 |
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HC Growth Medium wo Phenol Red: Growth medium without phenol red |
500 ml | 411PR-500 |
| HC Differentiation Medium wo Phenol Red: Promotes cells to change from one type to another, more specialized, without Phenol Red | 250 ml | 411DPR-250 |
EXTENDED FAMILY PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Freezing Medium: For general cryopreservation of most primary cells. Contains FBS & DMSO. | 50 ml | 040-50 |
| Human Connective Tissue Growth Factor (CTGF): Human Connective Tissue Growth Factor | 20 ug | RP1060-20 |
| Human Connective Tissue Growth Factor (CTGF): Human Connective Tissue Growth Factor | 100 ug | RP1060-100 |
| Human Connective Tissue Growth Factor (CTGF): Human Connective Tissue Growth Factor | 1000 ug | RP1060-1000 |
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Cyto-X Cell Counting Reagent: 500 tests |
1 Bottle | 028-01 |
| Cyto-X Cell Counting Reagent Sample: 100 tests | Sample | 028-S |
| Cytofect™ Chondrocyte Transfection Kit: 175 x 24-Well Rxns | 1 Kit | TF402K |
| Cytofect™ Chondrocyte Transfection Kit: 25 x 24-Well Rxns | 1 Sample Kit | TF402KS |
| HC, Re-Differentiated RNA, Adult: Total RNA prepared from Human Chondrocytes, Re-Differentiated, adult | 10 ul | 402RD-R10a |
| HC, Re-Differentiated RNA, Adult: Total RNA prepared from Human Chondrocytes, Re-Differentiated, adult | 25 ul | 402RD-R25a |
| HC, Re-Differentiated RNA, Fetal: Total RNA prepared from Human Chondrocytes, Re-Differentiated, fetal | 10 ul | 402RD-R10f |
| HC, Re-Differentiated RNA, Fetal: Total RNA prepared from Human Chondrocytes, Re-Differentiated, fetal | 25 ul | 402RD-R25f |
| Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | 1 Kit | 090K |